Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02CLU
|
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| Former ID |
DIB007342
|
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| Drug Name |
DNA vaccine
|
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| Synonyms |
DNA vaccine (melanoma); DNA vaccine (cancer), Memorial Sloan-Kettering Cancer Center; DNA vaccine (melanoma), Memorial Sloan-Kettering Cancer Center
|
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| Drug Type |
Vaccine
|
||||
| Indication | Melanoma [ICD9: 172; ICD10:C43] | Phase 1 | [1] | ||
| Company |
Memorial Sloan-Kettering Cancer Center
|
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| Target and Pathway | |||||
| Target(s) | Tyrosine oxidase | Target Info | [1] | ||
| BioCyc Pathway | (S)-reticuline biosynthesis | ||||
| Eumelanin biosynthesis | |||||
| L-dopachrome biosynthesis | |||||
| KEGG Pathway | Tyrosine metabolism | ||||
| Riboflavin metabolism | |||||
| Metabolic pathways | |||||
| Melanogenesis | |||||
| PathWhiz Pathway | Riboflavin Metabolism | ||||
| Tyrosine Metabolism | |||||
| WikiPathways | Dopamine metabolism | ||||
| References | |||||
| REF 1 | Safety and immunogenicity of tyrosinase DNA vaccines in patients with melanoma. Mol Ther. 2007 Nov;15(11):2044-50. Epub 2007 Aug 28. | ||||
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