Drug Information

Drug General Information
Drug ID
D02BOG
Former ID
DNC014236
Drug Name
H-Tyr(OMe)-Phe(2-Me)-NH2
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530745]
Structure
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2D MOL

3D MOL
Formula
C20H25N3O3
Canonical SMILES
CC1=CC=CC=C1CC(C(=O)N)NC(=O)C(CC2=CC=C(C=C2)OC)N
InChI
1S/C20H25N3O3/c1-13-5-3-4-6-15(13)12-18(19(22)24)23-20(25)17(21)11-14-7-9-16(26-2)10-8-14/h3-10,17-18H,11-12,21H2,1-2H3,(H2,22,24)(H,23,25)/t17-,18-/m0/s1
InChIKey
DZDNCKHJPMLWQZ-ROUUACIJSA-N
PubChem Compound ID
45379600
Target and Pathway
Target(s) Substance-P receptor Target Info Inhibitor [530745]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Measles
PANTHER Pathway CCKR signaling map ST
Reactome G alpha (q) signalling events
WikiPathways SIDS Susceptibility Pathways
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 530745J Med Chem. 2010 Mar 25;53(6):2383-9.Discovery of dipeptides with high affinity to the specific binding site for substance P1-7.
Ref 530745J Med Chem. 2010 Mar 25;53(6):2383-9.Discovery of dipeptides with high affinity to the specific binding site for substance P1-7.

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