Drug Information

Drug General Information
Drug ID
D02ANZ
Former ID
DIB020707
Drug Name
phenylacetylrinvanil
Synonyms
PhAR; IDN5890
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467621]
Structure
Download
2D MOL
Formula
C34H49NO4
InChI
InChI=1S/C34H49NO4/c1-3-4-5-15-20-30(32(37)25-28-18-13-12-14-19-28)21-16-10-8-6-7-9-11-17-22-34(38)35-27-29-23-24-31(36)33(26-29)39-2/h10,12-14,16,18-19,23-24,26,30,36H,3-9,11,15,17,20-22,25,27H2,1-2H3,(H,35,38)/b16-10-/t30-/m1/s1
InChIKey
STBVSPCCKFGBHG-DJVRBGHSSA-N
PubChem Compound ID
73852566
PubChem Substance ID
178101100
Target and Pathway
Target(s) Vanilloid receptor 1 Target Info Activator [527206]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channels
References
Ref 467621(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4283).
Ref 527206Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential. J Pharmacol Exp Ther. 2005 Feb;312(2):561-70. Epub 2004 Sep 8.

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