Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02ACL
|
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| Former ID |
DIB018958
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| Drug Name |
benzamil
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [467490] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C13H14ClN7O
|
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| InChI |
InChI=1S/C13H14ClN7O/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22)
|
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| InChIKey |
KXDROGADUISDGY-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
586340, 621649, 4997149, 11110839, 11110840, 11120241, 11120729, 11121217, 11121645, 11122125, 11336176, 11361415, 11362714, 11365276, 11367838, 11370699, 11370700, 11373064, 11373439, 11376000, 11462387, 11466685, 11467805, 11486350, 11491638, 15248269, 26755660, 26755661, 44437002, 47870415, 47870416, 48019678, 48019679, 48095241, 48244091, 48318723, 48319195, 48319196, 48394633, 49698609, 50068048, 50110974, 50110975, 50686741, 53849316, 57338445, 85787710, 85787961, 90341795, 92309106
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| Target and Pathway | |||||
| Target(s) | ENaCalphabetagamma | Target Info | Blocker (channel blocker) | [543954] | |
| TRPP2 | Target Info | Blocker (channel blocker) | [543860] | ||
| Acid-sensing ion channel ASIC3 | Target Info | Blocker (channel blocker) | [543913] | ||
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | ||||
| Reactome | Stimuli-sensing channels | ||||
| WikiPathways | Iron uptake and transport | ||||
| References | |||||
| Ref 543860 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 505). | ||||
| Ref 543913 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 684). | ||||
| Ref 543954 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 742). | ||||
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