TTD | Drug: D01WJM

Drug General Information
Drug ID	D01WJM
Former ID	DIB016677
Drug Name	D-26344
Indication	Cancer [ICD9: 140-229; ICD10:C00-C96]		Terminated	[547135]
Company	ASTA Medica AG
Structure		Download 2D MOL 3D MOL
Canonical SMILES	N1(C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC<br />(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)C)<br />Cc2cc3c(cc2)cccc3)Cc2ccc(Cl)cc2)Cc2cnccc2)CO)Cc2ccc(cc2<br />)O)CCCCNC(=O)CCC(=O)Nc2ccc(C(=N)N)cc2)CC(C)C)CCCNC(=N)N<br />)[C@H](C(=O)N[C@@H](C(=O)N)C)CCC1
CAS Number	CAS 191611-37-7
Target and Pathway
Target(s)	Gonadotropin-releasing hormone receptor	Target Info	Inhibitor	[545436]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	GnRH signaling pathway
NetPath Pathway	IL1 Signaling Pathway
NetPath Pathway	IL2 Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Hormone ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 547135	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013297)
Ref 545436	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003256)

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Drug Information