Drug General Information
Drug ID	D01VNL
Former ID	DIB012441
Drug Name	JM-1232(-)
Synonyms	Sedative, Maruishi; Benzodiazepine agonist (sedation), Maruishi
Indication	Anesthesia [ICD9: 338; ICD10:R20.0]		Investigative	[543814]
Company	Maruishi Pharmaceutical Co Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	O=C1c2cc3c(cc2[C@H](N1c1ccccc1)CC(=O)N1CCN(CC1)C)CCC3
Target and Pathway
Target(s)	GABA A receptor	Target Info	Agonist	[543814]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 543814	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415).
Ref 543814	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415).

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