Drug Information
Drug General Information | |||||
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Drug ID |
D01TKB
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Former ID |
DCL000377
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Drug Name |
GSK424887
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Drug Type |
Small molecular drug
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Indication | Depression; Anxiety [ICD9: 300, 311; ICD10:F30-F39, F40-F42] | Discontinued in Phase 1 | [548690] | ||
Company |
GSK
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Structure |
Download2D MOL |
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Formula |
C33H44N6O5
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Canonical SMILES |
CC(C)CC(C(=O)NC(CC1=CN(C2=CC=CC=C21)C)C(=O)NC(CC3=CC=CC<br />=N3)C(=O)O)NC(=O)N4CCCCCC4
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InChI |
1S/C33H44N6O5/c1-22(2)18-26(37-33(44)39-16-10-4-5-11-17-39)30(40)35-27(19-23-21-38(3)29-14-7-6-13-25(23)29)31(41)36-28(32(42)43)20-24-12-8-9-15-34-24/h6-9,12-15,21-22,26-28H,4-5,10-11,16-20H2,1-3H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43)/t26-,27+,28+/m0/s1
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InChIKey |
LIOKMIQQPDDTNO-UPRLRBBYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Substance-P receptor | Target Info | Antagonist | [550963] | |
PANTHER Pathway | CCKR signaling map ST | ||||
Reactome | G alpha (q) signalling events | ||||
References |
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