Drug General Information
Drug ID
D01SBP
Former ID
DIB014553
Drug Name
Co-152791
Indication Epilepsy [ICD10:G40] Terminated [546908]
Company
Purdue Neuroscience Corp
Structure
Download
2D MOL

3D MOL

Canonical SMILES
[C@@]12([C@H]([C@H]3[C@@H]([C@@]4([C@H](C[C@@](C#Cc5ccc<br />(C(=O)C)cc5)(CC4)O)CC3)C)CC2)CC[C@@H]1C(=O)C)C
CAS Number
CAS 162882-63-5
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [534715]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 546908Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011029)
Ref 534715Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors. J Pharmacol Exp Ther. 1998Oct;287(1):198-207.

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