Drug Information
Drug General Information | |||||
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Drug ID |
D01RNA
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Former ID |
DIB019718
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Drug Name |
desmosterol
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539793] | ||
Structure |
Download2D MOL |
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Formula |
C27H44O
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InChI |
InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
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InChIKey |
AVSXSVCZWQODGV-DPAQBDIFSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
4928, 4266377, 8144027, 10298383, 15978228, 24894033, 36883775, 52670367, 57394893, 57403092, 99300578, 103637422, 104620858, 126524635, 127466210, 135651470, 137237337, 138128789, 138613691, 162221242, 164815728, 179293074, 184544358, 198962901, 223703363, 224772242, 226520608, 252363923, 252551927, 252669467
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Target and Pathway | |||||
Target(s) | Oxysterols receptor LXR-beta | Target Info | Agonist | [528328] | |
Farnesoid X receptor-beta | Target Info | Agonist | [526511] | ||
Oxysterols receptor LXR-alpha | Target Info | Agonist | [528328] | ||
References | |||||
Ref 526511 | Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol. Mol Cell Biol. 2003 Feb;23(3):864-72. | ||||
Ref 528328 | Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands. J Biol Chem. 2006 Sep 22;281(38):27816-26. Epub 2006 Jul 20. |
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