Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01NZS
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| Former ID |
DNC012210
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| Drug Name |
2-(6-Imidazol-1-yl-hexyl)-isoindole-1,3-dione
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C17H19N3O2
|
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=O)N(C2=O)CCCCCCN3C=CN=C3
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| InChI |
1S/C17H19N3O2/c21-16-14-7-3-4-8-15(14)17(22)20(16)11-6-2-1-5-10-19-12-9-18-13-19/h3-4,7-9,12-13H,1-2,5-6,10-11H2
|
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| InChIKey |
CGDDIOSGLRENCV-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Thromboxane-A synthase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | C20 prostanoid biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Platelet activation | |||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Prostaglandin Synthesis and Regulation | ||||
| Arachidonic acid metabolism | |||||
| Phase 1 - Functionalization of compounds | |||||
| Eicosanoid Synthesis | |||||
| References | |||||
| REF 1 | J Med Chem. 1986 May;29(5):816-9.Thromboxane synthetase inhibitors and antihypertensive agents. 2. N-[(1H-imidazol-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones and N-[(1H-1,2,4-triazol-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones as unique antihypertensive agents. | ||||
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