TTD | Drug: D01LRC

Drug General Information
Drug ID	D01LRC
Former ID	DNC008862
Drug Name	ANIBAMINE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527121]
Structure		Download 2D MOL 3D MOL
Formula	C32H50F3NO2
Canonical SMILES	CCCCCCCCC=CC1=C(C(=C([N+]2=C1CCC2)C)C=CCCCCCCCC)C.C(=O)<br />(C(F)(F)F)[O-]
InChI	1S/C30H50N.C2HF3O2/c1-5-7-9-11-13-15-17-19-22-28-26(3)29(30-24-21-25-31(30)27(28)4)23-20-18-16-14-12-10-8-6-2;3-2(4,5)1(6)7/h19-20,22-23H,5-18,21,24-25H2,1-4H3;(H,6,7)/q+1;/p-1/b22-19-,23-20-;
InChIKey	IMNADGBFDKRXGY-HDZLQULISA-M
PubChem Compound ID	11387106
Target and Pathway
Target(s)	C-C chemokinereceptor type 5	Target Info	Inhibitor	[527121]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway
	Endocytosis
	Toxoplasmosis
	Viral carcinogenesis
NetPath Pathway	TSLP Signaling Pathway
	TCR Signaling Pathway
	IL2 Signaling Pathway
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database	IL12-mediated signaling events
Reactome	Binding and entry of HIV virion
	Chemokine receptors bind chemokines
	G alpha (i) signalling events
WikiPathways	TCR Signaling Pathway
	GPCRs, Class A Rhodopsin-like
	HIV Life Cycle
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 527121	J Nat Prod. 2004 Jun;67(6):1036-8.Isolation and structure of antagonists of chemokine receptor (CCR5).
Ref 527121	J Nat Prod. 2004 Jun;67(6):1036-8.Isolation and structure of antagonists of chemokine receptor (CCR5).

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Drug Information