Drug Information
Drug General Information | |||||
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Drug ID |
D01HTL
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Former ID |
DAP000765
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Drug Name |
Vinorelbine
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Synonyms |
Eunades; Exelbine; NVB; Navelbine; Vinorelbin; Vinorelbina; Vinorelbinum; Navelbine base; Vinorelbina [Spanish]; Vinorelbine Ditartarate; Vinorelbine ditartrate; Vinorelbine tartrate; Vinorelbinum [Latin]; KW 2307; KW 2307 base; ANX-530; KW-2307; Navelbine (TN); SDP-012; Vinorelbine (INN); Vinorelbine [INN:BAN]; Aspidospermidine-3-carboxylic acid; Nor-5'-anhydrovinblastine; Methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-acetoxy-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate; Methyl (2b,3b,4b,5a,12b,19a)-4-(acetyloxy)-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate
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Drug Type |
Small molecular drug
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Therapeutic Class |
Anticancer Agents
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Company |
GlaxoSmithKline
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Structure |
Download2D MOL |
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Formula |
C45H54N4O8
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InChI |
InChI=1S/C45H54N4O8/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3/t28-,37-,38+,39+,42+,43+,44-,45-/m0/s1
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InChIKey |
GBABOYUKABKIAF-IELIFDKJSA-N
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CAS Number |
CAS 71486-22-1
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PubChem Compound ID | |||||
PubChem Substance ID |
7980885, 11056542, 12013497, 16335940, 39341162, 56311577, 56312628, 57288872, 57359504, 78753678, 85670095, 92309089, 96025363, 99031250, 119526325, 124893200, 135049333, 136123131, 137001869, 152258373, 152344178, 160647210, 162011810, 162178830, 162224736, 163312394, 164831120, 175266041, 175608041, 176484268, 178103682, 179116945, 203356012, 226396694, 241376439, 252157261, 252359089
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SuperDrug ATC ID |
L01CA04
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SuperDrug CAS ID |
cas=071486221
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Target and Pathway | |||||
Target(s) | Tubulin | Target Info | Inhibitor | [536782] | |
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 542112 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7105). |
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