Drug Information
Drug General Information | |||||
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Drug ID |
D01FGR
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Former ID |
DAP000490
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Drug Name |
Diphenhydramine
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Synonyms |
Aleryl; Alledryl; Allerdryl; Allergeval; Allergical; Allergina; Allergival; Amidryl; Antistominum; Antitussive; Antomin; Automin; Bagodryl; Banophen; Baramine; Beldin; Belix; Bena; Benachlor; Benadrin; Benadryl; Benapon; Benhydramin; Benodin; Benodine; Benylan; Benylin; Benzantine; Benzhydramine; Benzhydraminum; Benzhydril; Benzhydroamina; Benzhydryl; Betramin; Compoz; Dabylen; Debendrin; Dermistina; Dermodrin; Desentol; Diabenyl; Diabylen; Dibendrin; Dibenil; Dibondrin; Difedryl; Difenhidramina; Difenhydramin; Difenidramina; Dihidral; Dimedrol; Dimedryl; Dimehydrinate; Diphantine; Diphen; Diphenhist; Diphenhydraminum; Diphenylhydramin; Diphenylhydramine; Dryistan; Drylistan; Dylamon; Etanautine; Genahist; Histaxin; Hyadrine; Hydramine; Hyrexin; Ibiodral; Medidryl; Mephadryl; Nausen; Novamina; Probedryl; Restamin; Rigidil; Siladryl; Silphen; Syntedril; Syntodril; Allergan B; Allermax Caplets; BENADRYL HCl; Banophen Caplets; Benadryl Allergy; Difenidramina [Italian]; Dimedrol base; Diphen Cough; Diphenhist Captabs; Diphenhydramine Base; Diphenhydramine HCl; Nytol Quickcaps; Nytol Quickgels;Twilite Caplets; Unisom Sleepgels Maximum Strength; Dormarex 2; FAR 90X2; PM 255; S51; Aller-Med; Ben-allergin; Benadryl (TN); Benadryl (hydrochloride); Beta-Dimethylaminoethanol diphenylmethyl ether; Beta-Dimethylaminoethylbenzhydrylether; Beta-dimethylaminoethyl benzhydryl ether; Difenhidramina [INN-Spanish]; Dimedrol (TN); Diphenhydraminum [INN-Latin]; Nervine Nighttime Sleep-Aid; Nytol (TN); O-Benzhydryldimethylaminoethanol; Restamin (TN); Sleep-Eze D; Sleep-Eze D Extra Strength; DIPHENHYDRAMINE, ANTISTOMINUM, BENZHYDRAMINE; Diphenhydramine (JP15/INN); Diphenhydramine [INN:BAN:JAN]; Alpha-(2-Dimethylaminoethoxy)diphenylmethane; N-(Benzhydryloksy-etylo)dwumetyloamina; N-(Benzhydryloksy-etylo)dwumetyloamina [Polish]; Beta-Dimethylamino-aethyl-benzhydryl-aether; Beta-Dimethylamino-aethyl-benzhydryl-aether [German]; N,N-Dimethyl-2-(diphenylmethoxy)-ethylamine hydrochloride; N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE; N-(2-(Diphenylmethoxy)ethyl)-N,N-dimethylamine; 2-(Benzhydryloxy)-N,N-dimethylethylamine; 2-(Benzhydryloxy)-N,N-dimethylethylamine, hydrochloride; 2-(Diphenylmethoxy)-N,N-dimethylethylamine; 2-(diphenylmethoxy)-N,N-dimethylethanamine; 2-Diphenylmethoxy-N,N-dimethylethylamine; 2-[(diphenylmethyl)oxy]-N,N-dimethylethanamine; 2-benzhydryloxy-N,N-dimethylethanamine; 2-benzhydryloxyethyl-N,N-dimethylammonium; 2-diphenylmethoxy-N,N-demthylethanamine; 2PM
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Drug Type |
Small molecular drug
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Indication | Vertigo's disease; Meniere's disease [ICD10:H81.09] | Approved | [551871] | ||
Therapeutic Class |
Antiallergic Agents
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Company |
Johnson & Johnson
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Structure |
Download2D MOL |
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Formula |
C17H21NO
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InChI |
InChI=1S/C17H21NO/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3
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InChIKey |
ZZVUWRFHKOJYTH-UHFFFAOYSA-N
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CAS Number |
CAS 58-73-1
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PubChem Compound ID | |||||
PubChem Substance ID |
9174, 511392, 608048, 3154507, 5021578, 7847366, 7849634, 7885212, 7979103, 8151972, 10508422, 10528411, 10544720, 11111059, 11111060, 11335543, 11360782, 11363874, 11366436, 11368998, 11371539, 11374238, 11377160, 11407308, 11427137, 11461754, 11466093, 11467213, 11484697, 11485906, 11488777, 11490216, 11492335, 11494794, 14749996, 25768169, 26713829, 26751623, 29222243, 46505484, 47440177, 47588927, 47810670, 47810671, 48035032, 48110379, 48110380, 48184925, 48184926, 48415909
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SuperDrug ATC ID |
D04AA32; R06AA02
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SuperDrug CAS ID |
cas=000058731
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Target and Pathway | |||||
Target(s) | Histamine H1 receptor | Target Info | Antagonist | [534958], [536700] | |
PANTHER Pathway | Histamine H1 receptor mediated signaling pathway | ||||
References | |||||
Ref 534958 | Histamine as an autocrine regulator of leukemic cell proliferation. Leuk Lymphoma. 2000 Jan;36(3-4):367-73. | ||||
Ref 536700 | Intact cell binding for in vitro prediction of sedative and non-sedative histamine H1-receptor antagonists based on receptor internalization. J Pharmacol Sci. 2008 May;107(1):66-79. Epub 2008 Apr 29. |
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