Drug Information
Drug General Information | |||||
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Drug ID |
D01DBQ
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Former ID |
DAP000651
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Drug Name |
Teniposide
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Synonyms |
PTG; Teniposido; Teniposidum; Vehem; Vumon; Demethyl Epipodophyllotoxin Thenylidine Glucoside; VM 26; Teniposido [INN-Spanish]; Teniposidum [INN-Latin]; VM-26; Vee M-26; Veham-Sandoz; Vumon (TN); Teniposide (USAN/INN); Teniposide [USAN:BAN:INN]; VM-26 (TN); Vumon, VM-26, Vehem, NSC 122819, Teniposide; Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-2-thenylidene-beta-D-glucopyranoside); 4'-Demethyl-epipodophyllotoxin-beta-D-thenylidene-glucoside; 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside); 4'-Demethylepipodophyllotoxin 9-(4,6-O-2-thenylidene-beta-D-glucopyranoside); 4'-Demethylepipodophyllotoxin thenylidene glucoside; 4'-Demethylepipodophyllotoxin-beta-D-thenylidine glucoside; 4'-Dimethyl-9-(4,6-O-2-thenyid)-epipodophyllotoxin; 4-Demethylepipodophyllotoxin-.beta.-D-thenylideneglucoside
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Drug Type |
Small molecular drug
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Therapeutic Class |
Anticancer Agents
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Structure |
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Download2D MOL |
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Formula |
C32H32O13S
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InChI |
InChI=1S/C32H32O13S/c1-37-19-6-13(7-20(38-2)25(19)33)23-14-8-17-18(42-12-41-17)9-15(14)28(16-10-39-30(36)24(16)23)44-32-27(35)26(34)29-21(43-32)11-40-31(45-29)22-4-3-5-46-22/h3-9,16,21,23-24,26-29,31-35H,10-12H2,1-2H3/t16-,21+,23+,24-,26+,27+,28+,29+,31+,32-/m0/s1
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InChIKey |
NRUKOCRGYNPUPR-QBPJDGROSA-N
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CAS Number |
CAS 29767-20-2
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PubChem Compound ID | |||||
PubChem Substance ID |
597750, 7980753, 10300907, 14912717, 49965048, 51063681, 53788607, 57405354, 99030090, 99246079, 103589230, 104253379, 104645164, 118046116, 119526326, 124757497, 125164301, 135692278, 136178636, 137001864, 139137932, 140852399, 152035492, 162037723, 162174797, 163620769, 163686094, 175267905, 176484801, 178103449, 179116911, 184811965, 187072639, 223384958, 226396002, 241050196, 251887699, 252220258, 252390155, 252401148, 252451125
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SuperDrug ATC ID |
L01CB02
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SuperDrug CAS ID |
cas=029767202
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Drug Resistance Mutation (DRM) | |||||
DRM | DRM Info | ||||
Target and Pathway | |||||
Target(s) | DNA topoisomerase II | Target Info | Modulator | [556264] | |
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 541923 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6843). |
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