Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01CYI
|
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| Former ID |
DNC006397
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| Drug Name |
7-hydroxy-3-(4-hydroxyphenyl)-3H-quinazolin-4-one
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C14H10N2O3
|
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| Canonical SMILES |
C1=CC(=CC=C1N2C=NC3=C(C2=O)C=CC(=C3)O)O
|
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| InChI |
1S/C14H10N2O3/c17-10-3-1-9(2-4-10)16-8-15-13-7-11(18)5-6-12(13)14(16)19/h1-8,17-18H
|
||||
| InChIKey |
NECCEJFVHJYYDA-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Estrogen receptor beta | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Estrogen signaling pathway | ||||
| Prolactin signaling pathway | |||||
| Pathway Interaction Database | Plasma membrane estrogen receptor signaling | ||||
| Validated nuclear estrogen receptor beta network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Reactome | Nuclear Receptor transcription pathway | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Ovarian Infertility Genes | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | J Med Chem. 2006 Apr 20;49(8):2440-55.Synthesis and characterization of 3-arylquinazolinone and 3-arylquinazolinethione derivatives as selective estrogen receptor beta modulators. | ||||
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