Drug General Information
Drug ID
D00WVW
Former ID
DNAP001707
Drug Name
YM443
Synonyms
Acofide; Acotiamide
Drug Type
Small molecular drug
Indication Upper abdominal bloating; Early satiation associated with functional dyspepsia [ICD9: 536.8; ICD10:K30] Approved [551871]
Company
Astellas
Structure
Download
2D MOL

3D MOL

Formula
C21H30N4O5S
Canonical SMILES
CC(C)N(CCNC(=O)C1=CSC(=N1)NC(=O)C2=CC(=C(C=C2O)OC)OC)C(<br />C)C
InChI
1S/C21H30N4O5S/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26/h9-13,26H,7-8H2,1-6H3,(H,22,28)(H,23,24,27)
InChIKey
TWHZNAUBXFZMCA-UHFFFAOYSA-N
CAS Number
CAS 185106-16-5
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Acetylcholinesterase Target Info Modulator [551871]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.