Drug General Information
Drug ID
D00WHO
Former ID
DNC014568
Drug Name
Ro-15-3505
Synonyms
Sarmazenil
Drug Type
Small molecular drug
Indication Discovery agent Terminated [546017]
Structure
Download
2D MOL

3D MOL

Formula
C15H14ClN3O3
Canonical SMILES
CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)Cl)C
InChI
1S/C15H14ClN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
InChIKey
QORLMYYHZLDYOR-UHFFFAOYSA-N
CAS Number
CAS 78771-13-8
PubChem Compound ID
Target and Pathway
Target(s) GABA A receptor Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 546017Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005900)

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