Drug Information

Drug General Information
Drug ID
D00UDP
Former ID
DCL001082
Drug Name
Terameprocol
Synonyms
EM-1421; Terameprocol (INN/USAN); Meso-Tetra-O-methylnordihydroguaiaretic acid; Meso-Tetramethoxy-4,4'-(2,3-dimethyltetramethylene)dipyrocatechol; Meso-1,4-Bis-(3,4-dimethoxyphenyl)-2,3-dimethylbutane; 4-[(2S,3R)-4-(3,4-dimethoxyphenyl)-2,3-dimethylbutyl]-1,2-dimethoxybenzene
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 2 [529346]
Company
Erimos
Structure
Download
2D MOL

3D MOL
Formula
C22H30O4
Canonical SMILES
CC(CC1=CC(=C(C=C1)OC)OC)C(C)CC2=CC(=C(C=C2)OC)OC
InChI
1S/C22H30O4/c1-15(11-17-7-9-19(23-3)21(13-17)25-5)16(2)12-18-8-10-20(24-4)22(14-18)26-6/h7-10,13-16H,11-12H2,1-6H3/t15-,16+
InChIKey
ORQFDHFZSMXRLM-IYBDPMFKSA-N
CAS Number
CAS 5701-82-6
PubChem Compound ID
476861
PubChem Substance ID
634229, 10308365, 14876677, 38928519, 60344639, 78001023, 96025697, 103297437, 109720634, 128851936, 135207316, 140825714, 162247357, 162972096, 172918313, 174007437, 186000970, 198955324, 221678794, 223405961, 223704956, 226553371, 250136785, 252469451
Target and Pathway
Target(s) Transcription factor Sp1 Target Info Modulator [529346]
References
Ref 529346Terameprocol, a novel site-specific transcription inhibitor with anticancer activity. IDrugs. 2008 Mar;11(3):204-14.
Ref 529346Terameprocol, a novel site-specific transcription inhibitor with anticancer activity. IDrugs. 2008 Mar;11(3):204-14.

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