Drug Information

Drug General Information
Drug ID
D00TRV
Former ID
DNAP001681
Drug Name
Besifloxacin
Synonyms
Besivance (TN)
Drug Type
Small molecular drug
Indication Ocular inflammation [ICD9: 370.33; ICD10:H16.229] Approved [530677], [531950]
Company
Bausch & Lomb
Structure
Download
2D MOL

3D MOL
Formula
C19H21ClFN3O3
Canonical SMILES
C1CCN(CC(C1)N)C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4CC4)<br />F
InChI
1S/C19H21ClFN3O3/c20-15-16-12(18(25)13(19(26)27)9-24(16)11-4-5-11)7-14(21)17(15)23-6-2-1-3-10(22)8-23/h7,9-11H,1-6,8,22H2,(H,26,27)/t10-/m1/s1
InChIKey
QFFGVLORLPOAEC-SNVBAGLBSA-N
CAS Number
CAS 141388-76-3
PubChem Compound ID
10178705
PubChem Substance ID
15174158, 22574230, 40268281, 75022188, 109693082, 124960920, 126616793, 126666799, 131270818, 135260940, 138035720, 164043533, 175265578, 175427091, 223392224, 223658983, 227014124, 245552661, 252431687, 252562110
SuperDrug ATC ID
S01AE08
Target and Pathway
Target(s) Bacterial DNA gyrase Target Info Modulator [530677], [531950]
Topoisomerase IV Target Info Modulator [530677], [531950]
References
Ref 530677Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
Ref 531950Besifloxacin ophthalmic suspension, 0.6%: a novel topical fluoroquinolone for bacterial conjunctivitis. Adv Ther. 2012 Jun;29(6):473-90.
Ref 530677Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
Ref 531950Besifloxacin ophthalmic suspension, 0.6%: a novel topical fluoroquinolone for bacterial conjunctivitis. Adv Ther. 2012 Jun;29(6):473-90.

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