Drug General Information
Drug ID
D00ORM
Former ID
DNC005041
Drug Name
5-Carbazol-9-yl-pentanoic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527208]
Structure
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2D MOL

3D MOL

Formula
C17H17NO2
Canonical SMILES
C1=CC=C2C(=C1)C3=CC=CC=C3N2CCCCC(=O)O
InChI
1S/C17H17NO2/c19-17(20)11-5-6-12-18-15-9-3-1-7-13(15)14-8-2-4-10-16(14)18/h1-4,7-10H,5-6,11-12H2,(H,19,20)
InChIKey
YEPJVQJMLQBLOE-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Fatty acid-bindingprotein, epidermal Target Info Inhibitor [527208]
Fatty acid-binding protein, adipocyte Target Info Inhibitor [527208]
KEGG Pathway PPAR signaling pathwayhsa03320:PPAR signaling pathway
NetPath Pathway IL1 Signaling PathwayNetPath_11:TCR Signaling Pathway
Pathway Interaction Database AP-1 transcription factor network
Reactome Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysisR-HSA-163560:Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
Transcriptional regulation of white adipocyte differentiation
WikiPathways Lipid digestion, mobilization, and transport
Transcriptional Regulation of White Adipocyte Differentiation
References
Ref 527208Bioorg Med Chem Lett. 2004 Sep 6;14(17):4445-8.Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target.
Ref 527208Bioorg Med Chem Lett. 2004 Sep 6;14(17):4445-8.Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target.

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