| Drug General Information |
| Drug ID |
D00OLH
|
| Former ID |
DNC004007
|
| Drug Name |
4-[1,2-bis(4-hydroxyphenyl)vinyl]phenol
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C20H16O3
|
| Canonical SMILES |
C1=CC(=CC=C1C=C(C2=CC=C(C=C2)O)C3=CC=C(C=C3)O)O
|
| InChI |
1S/C20H16O3/c21-17-7-1-14(2-8-17)13-20(15-3-9-18(22)10-4-15)16-5-11-19(23)12-6-16/h1-13,21-23H
|
| InChIKey |
LZHPXIZTZSFAAE-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Estrogen receptor beta |
Target Info |
Inhibitor |
[1]
|
|---|
| Estrogen receptor |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
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Estrogen signaling pathway
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Prolactin signaling pathwayhsa04915:Estrogen signaling pathway
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Prolactin signaling pathway
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Thyroid hormone signaling pathway
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Endocrine and other factor-regulated calcium reabsorption
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Proteoglycans in cancer
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NetPath Pathway
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FSH Signaling Pathway
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EGFR1 Signaling Pathway
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RANKL Signaling Pathway
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Pathway Interaction Database
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Plasma membrane estrogen receptor signaling
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Validated nuclear estrogen receptor beta network
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Validated nuclear estrogen receptor alpha networksmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
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Signaling events mediated by HDAC Class II
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LKB1 signaling events
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Regulation of Telomerase
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ATF-2 transcription factor network
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AP-1 transcription factor network
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FOXM1 transcription factor network
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Validated nuclear estrogen receptor alpha network
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Signaling mediated by p38-alpha and p38-beta
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FOXA1 transcription factor network
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Reactome
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Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
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Nuclear Receptor transcription pathway
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WikiPathways
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SIDS Susceptibility Pathways
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Ovarian Infertility Genes
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Integrated Pancreatic Cancer Pathway
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Nuclear ReceptorsWP712:Estrogen signaling pathway
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Nuclear Receptors Meta-Pathway
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Estrogen Receptor Pathway
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Signaling by ERBB4
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JAK/STAT
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Leptin signaling pathway
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miR-targeted genes in muscle cell - TarBase
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Integrated Breast Cancer Pathway
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Nuclear Receptors
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| References |
| REF 1 | J Med Chem. 2003 Apr 10;46(8):1484-91.Antiestrogenically active 1,1,2-tris(4-hydroxyphenyl)alkenes without basic side chain: synthesis and biological activity. |
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