Drug Information
Drug General Information | |||||
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Drug ID |
D00OAW
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Former ID |
DIB009350
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Drug Name |
DHEA
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Synonyms |
Dehydroepiandrosterone; Fidelin; DHEA, Neuroscience Pharma; DHEA, Paladin Labs; Dehydroepiandrosterone, Neuroscience Pharma; Dehydroepiandrosterone, Paladin Labs
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Drug Type |
Small molecular drug
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Company |
Aeson Therapeutics Tucson; AZ
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Structure |
Download2D MOL |
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Formula |
C19H28O2
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InChI |
InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1
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InChIKey |
FMGSKLZLMKYGDP-USOAJAOKSA-N
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CAS Number |
CAS 53-43-0
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PubChem Compound ID | |||||
PubChem Substance ID |
1983, 4449, 75250, 596018, 837865, 841442, 3135651, 7885884, 8145544, 8153636, 11446567, 12014907, 12146065, 14751238, 14775640, 17404931, 24278369, 24702275, 26703947, 29224908, 46387028, 46508824, 47193749, 47959958, 48413520, 48415849, 49681751, 49747225, 49857278, 50172721, 53777474, 53788218, 56312069, 56312916, 56313484, 56313819, 56320669, 56320670, 57323014, 87566797, 91692812, 92297484, 92303742, 92308678, 92309040, 92709895, 93167098, 96025095, 103302695, 104095449
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Target and Pathway | |||||
Target(s) | Androgen receptor | Target Info | Antagonist | [525358] | |
Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
Coregulation of Androgen receptor activity | |||||
Regulation of Androgen receptor activity | |||||
Nongenotropic Androgen signaling | |||||
Regulation of nuclear beta catenin signaling and target gene transcription | |||||
FOXA1 transcription factor network | |||||
Notch-mediated HES/HEY network | |||||
References | |||||
Ref 525084 | ClinicalTrials.gov (NCT02357472) The Effect of a Higher Dose of Dehydroepiandrosterone (DHEA) Supplementation in Poor Responders. U.S. National Institutes of Health. | ||||
Ref 539508 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2370). |
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