Drug Information

Drug General Information
Drug ID
D00NJJ
Former ID
DAP001180
Drug Name
Mezlocillin
Synonyms
Mezlin; Mezlocilina; Mezlocillinum; Mezlocillin (USAN/INN); (2S,5R,6R)-3,3-dimethyl-6-[[(2R)-2-[(3-methylsulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylic acid; 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid
Drug Type
Small molecular drug
Indication Urinary tract infections [ICD9: 599; ICD10:N39.0] Approved [538601], [551871]
Therapeutic Class
Antibiotics
Structure
Download
2D MOL

3D MOL
Formula
C21H25N5O8S2
Canonical SMILES
CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)NC(=O)N4CCN(C4=<br />O)S(=O)(=O)C)C(=O)O)C
InChI
1S/C21H25N5O8S2/c1-21(2)14(18(29)30)26-16(28)13(17(26)35-21)22-15(27)12(11-7-5-4-6-8-11)23-19(31)24-9-10-25(20(24)32)36(3,33)34/h4-8,12-14,17H,9-10H2,1-3H3,(H,22,27)(H,23,31)(H,29,30)/t12-,13-,14+,17-/m1/s1
InChIKey
YPBATNHYBCGSSN-VWPFQQQWSA-N
CAS Number
CAS 51481-65-3
PubChem Compound ID
656511
PubChem Substance ID
9430, 7979982, 9268054, 14812305, 46506692, 47206748, 48416275, 50112724, 57304812, 78885179, 103684353, 113527669, 124766347, 129827565, 131316906, 134223968, 134338425, 137003441, 144206027, 160964287, 162172976, 162177476, 163136009, 163414461, 163849319, 175442319, 179150528, 184544890, 196392849, 198944248, 206246064, 223398264, 223672045, 226420598, 249867216, 251891692, 251916660, 251917909, 252070744, 252358711
ChEBI ID
ChEBI:6919
SuperDrug ATC ID
J01CA10
SuperDrug CAS ID
cas=051481653
Target and Pathway
Target(s) Penicillin binding protein 3 Target Info Binder [537719]
References
Ref 538601FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 050549.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 537719Bactericidal effect of piperacillin alone and combined. Presse Med. 1986 Dec 20;15(46):2297-302.

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