Drug General Information
Drug ID
D00MZD
Former ID
DNC003449
Drug Name
7n-Methyl-8-Hydroguanosine-5'-Diphosphate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL

Formula
C11H19N5O11P2
Canonical SMILES
CN1CN(C2=C1C(=O)N=C(N2)N)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)<br />O)O)O
InChI
1S/C11H19N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h4,6-7,10,17-18H,2-3H2,1H3,(H,23,24)(H2,20,21,22)(H3,12,13,14,19)/t4-,6-,7-,10-/m1/s1
InChIKey
QQODJOAVWUWVHJ-KQYNXXCUSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) mRNA of Eukaryotic translation initiation factor 4E Target Info Inhibitor [551393]
KEGG Pathway RNA transport
HIF-1 signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
Insulin signaling pathway
PANTHER Pathway p38 MAPK pathway
CCKR signaling map ST
Pathway Interaction Database Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
Validated targets of C-MYC transcriptional activation
mTOR signaling pathway
Signaling mediated by p38-alpha and p38-beta
PathWhiz Pathway Leucine Stimulation on Insulin Signaling
Reactome ISG15 antiviral mechanism
mTORC1-mediated signalling
WikiPathways Interferon type I signaling pathways
Hypertrophy Model
Insulin Signaling
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
ISG15 antiviral mechanism
Deadenylation-dependent mRNA decay
Structural Pathway of Interleukin 1 (IL-1)
BDNF signaling pathway
Leptin signaling pathway
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
Signaling by Insulin receptor
Processing of Capped Intron-Containing Pre-mRNA
Eukaryotic Translation Initiation
Translation Factors
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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