Drug Information

Drug General Information
Drug ID
D00KOV
Former ID
DIB009135
Drug Name
Monatepil maleate
Synonyms
AD-2615; AJ-2615
Drug Type
Small molecular drug
Indication Angina pectoris [ICD9: 413; ICD10:I20] Discontinued in Preregistration [544922]
Company
Dainippon Pharmaceutical Co Ltd
Structure
Download
2D MOL

3D MOL
Formula
C32H34FN3O5S
Canonical SMILES
Fc1ccc(cc1)N2CCN(CCCC(=O)NC3c4ccccc4CSc5ccccc35)CC2
InChI
1S/C28H30FN3OS/c29-22-11-13-23(14-12-22)32-18-16-31(17-19-32)15-5-10-27(33)30-28-24-7-2-1-6-21(24)20-34-26-9-4-3-8-25(26)28/h1-4,6-9,11-14,28H,5,10,15-20H2,(H,30,33)
InChIKey
WFNRNNUZFPVBSM-UHFFFAOYSA-N
CAS Number
CAS 103379-03-9
PubChem Compound ID
5282401
Target and Pathway
Target(s) Calcium channel Target Info Modulator [533755]
References
Ref 544922Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001558)
Ref 533755Antihypertensive, antiatherosclerotic, and plasma lipid-lowering effects of monatepil, a novel calcium antagonist with alpha 1-adrenoceptor-blocking activity in experimental animals. Am J Hypertens. 1994 Oct;7(10 Pt 2):131S-40S.

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