Drug General Information
Drug ID
D00HVP
Former ID
DNC008417
Drug Name
Riccardin C
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529375]
Structure
Download
2D MOL

3D MOL

Formula
C28H24O4
Canonical SMILES
C1CC2=C(C=CC(=C2)O)C3=C(C=C(CCC4=CC(=C(C=C4)O)OC5=CC=C1<br />C=C5)C=C3)O
InChI
1S/C28H24O4/c29-22-9-13-24-21(17-22)8-3-18-4-10-23(11-5-18)32-28-16-20(7-14-26(28)30)2-1-19-6-12-25(24)27(31)15-19/h4-7,9-17,29-31H,1-3,8H2
InChIKey
JMKSVONWZFVEAI-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Oxysterols receptor LXR-beta Target Info Inhibitor [529375]
Oxysterols receptor LXR-alpha Target Info Inhibitor [529375]
KEGG Pathway PPAR signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hepatitis C
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor
Reactome Nuclear Receptor transcription pathway
WikiPathways SREBP signalling
Nuclear ReceptorsWP299:Nuclear Receptors in Lipid Metabolism and Toxicity
Nuclear Receptors Meta-Pathway
PPAR Alpha Pathway
Liver X Receptor Pathway
Adipogenesis
SREBF and miR33 in cholesterol and lipid homeostasis
Nuclear Receptors
References
Ref 529375Bioorg Med Chem. 2008 Apr 15;16(8):4272-85. Epub 2008 Feb 29.Co-existence of alpha-glucosidase-inhibitory and liver X receptor-regulatory activities and their separation by structural development.
Ref 529375Bioorg Med Chem. 2008 Apr 15;16(8):4272-85. Epub 2008 Feb 29.Co-existence of alpha-glucosidase-inhibitory and liver X receptor-regulatory activities and their separation by structural development.

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