Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00HNK
|
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| Former ID |
DIB006146
|
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| Drug Name |
RHb1.1
|
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| Synonyms |
Optro; Hemoglobin, Somatogen
|
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| Indication | Anemia [ICD9: 280-285; ICD10:D50-D64] | Terminated | [1] | ||
| Company |
Somatogen Inc
|
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| Target and Pathway | |||||
| Target(s) | Hemoglobin | Target Info | Modulator | [2] | |
| KEGG Pathway | African trypanosomiasis | ||||
| Malaria | |||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | ||||
| Erythrocytes take up oxygen and release carbon dioxide | |||||
| Scavenging of heme from plasma | |||||
| WikiPathways | Binding and Uptake of Ligands by Scavenger Receptors | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | |||||
| Factors involved in megakaryocyte development and platelet production | |||||
| Folate Metabolism | |||||
| Vitamin B12 Metabolism | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008362) | ||||
| REF 2 | Effects of recombinant-hemoglobin solutions rHb2.0 and rHb1.1 on blood pressure, intestinal blood flow, and gut oxygenation in a rat model of hemorrhagic shock. J Lab Clin Med. 2005 Jan;145(1):21-32. | ||||
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