TTD | Drug: D00GHK

Drug General Information
Drug ID	D00GHK
Former ID	DIB018472
Drug Name	13,14-dihydro-15-keto-PGD2
Synonyms	13,14-dihydro-15-keto-prostaglandin D2; 13,14-dihydro-15-ketoprostaglandin D2; DK-PGD2; 13,14-dihydro-15-oxo PGD2
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539201]
Structure		Download 2D MOL
Formula	C20H32O5
InChI	InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-18,22H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,18+/m1/s1
InChIKey	VSRXYLYXIXYEST-KZTWKYQFSA-N
PubChem Compound ID	5283036
PubChem Substance ID	4265966, 7979705, 11038695, 39316453, 50075763, 53351994, 53787923, 57358812, 113858904, 135191771, 135649648, 179656209, 184568154, 250132931, 252391956, 252457407, 252463985
Target and Pathway
Target(s)	Putative G-protein coupled receptor 44	Target Info	Agonist	[527831]
Reactome	Prostanoid ligand receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539201	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1900).
Ref 527831	CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses. Eur J Pharmacol. 2005 Nov 7;524(1-3):30-7. Epub 2005 Oct 27.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information