Drug Information

Drug General Information
Drug ID
DXZ1XN
Drug Name
1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-pyridin-2-yl-ethanone
Synonyms
CHEMBL341393
Indication Discovery agent Investigative [1587926]
Formula
C25H25ClN4O
Canonical SMILES
Clc1ccc2C(N3CCN(CC3)C(=O)Cc4ccccn4)c5ncccc5CCc2c1
InChI
InChI=1S/C25H25ClN4O/c26-20-8-9-22-19(16-20)7-6-18-4-3-11-28-24(18)25(22)30-14-12-29(13-15-30)23(31)17-21-5-1-2-10-27-21/h1-5,8-11,16,25H,6-7,12-15,17H2
InChIKey
KKXWFFNNTODCTJ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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