Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXZ0JB
|
||||
| Drug Name |
(S)-3-methyl-N-(4-methyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)pentan-2-yl)benzamide
|
||||
| Synonyms |
CHEMBL206050
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H28F3N3O3
|
||||
| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1cccc(C)c1)C(=O)NCCNc2ccc(OC(F)(F)F)cc2
|
||||
| InChI |
InChI=1S/C23H28F3N3O3/c1-15(2)13-20(29-21(30)17-6-4-5-16(3)14-17)22(31)28-12-11-27-18-7-9-19(10-8-18)32-23(24,25)26/h4-10,14-15,20,27H,11-13H2,1-3H3,(H,28,31)(H,29,30)/t20-/m0/s1
|
||||
| InChIKey |
NOGPDFYAILRYLC-FQEVSTJZSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.