Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXY4UP
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| Drug Name |
N-{(S)-2-Cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-4-(4,6-dimethyl-pyrimidin-2-ylamino)-benzamide
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| Synonyms |
CHEMBL194405
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C31H40N6O3
|
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| Canonical SMILES |
COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c3ccc(Nc4nc(C)cc(C)n4)cc3)cc1
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| InChI |
InChI=1S/C31H40N6O3/c1-21-19-22(2)35-31(34-21)36-26-11-9-24(10-12-26)29(38)37-28(20-23-7-5-4-6-8-23)30(39)33-18-17-32-25-13-15-27(40-3)16-14-25/h9-16,19,23,28,32H,4-8,17-18,20H2,1-3H3,(H,33,39)(H,37,38)(H,34,35,36)/t28-/m0/s1
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| InChIKey |
PRGVGZFPDSRIPJ-NDEPHWFRSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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