Drug Information

Drug General Information
Drug ID
DXY3DV
Drug Name
(S)-2-Amino-1-[4-(8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-3-(4-methoxy-benzylsulfanyl)-propan-1-one
Synonyms
CHEMBL329519
Indication Discovery agent Investigative [1587926]
Formula
C30H32ClN3O2S
Canonical SMILES
COc1ccc(CSC[C@@H](N)C(=O)N2CCC(=C3c4ccc(Cl)cc4CCc5cccnc35)CC2)cc1
InChI
InChI=1S/C30H32ClN3O2S/c1-36-25-9-4-20(5-10-25)18-37-19-27(32)30(35)34-15-12-21(13-16-34)28-26-11-8-24(31)17-23(26)7-6-22-3-2-14-33-29(22)28/h2-5,8-11,14,17,27H,6-7,12-13,15-16,18-19,32H2,1H3/t27-/m1/s1
InChIKey
HQBPLAXDCKDONK-HHHXNRCGSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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