Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXXO2B
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| Drug Name |
6-(4-chlorobenzylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile
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| Synonyms |
CHEMBL252934
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C16H15ClN6O
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| Canonical SMILES |
OCCCn1cnc2c(NCc3ccc(Cl)cc3)nc(nc12)C#N
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| InChI |
InChI=1S/C16H15ClN6O/c17-12-4-2-11(3-5-12)9-19-15-14-16(22-13(8-18)21-15)23(10-20-14)6-1-7-24/h2-5,10,24H,1,6-7,9H2,(H,19,21,22)
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| InChIKey |
YUWVGFWHMXEGHR-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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