Drug Information

Drug General Information
Drug ID
DXW9RH
Drug Name
1-(3-Chloro-phenyl)-4-[3-(2-methoxy-4'-trifluoromethyl-biphenyl-4-ylmethyl)-3H-imidazol-4-ylmethyl]-piperazin-2-one
Synonyms
CHEMBL277413
Indication Discovery agent Investigative [1587926]
Formula
C29H26ClF3N4O2
Canonical SMILES
COc1cc(Cn2cncc2CN3CCN(C(=O)C3)c4cccc(Cl)c4)ccc1c5ccc(cc5)C(F)(F)F
InChI
InChI=1S/C29H26ClF3N4O2/c1-39-27-13-20(5-10-26(27)21-6-8-22(9-7-21)29(31,32)33)16-36-19-34-15-25(36)17-35-11-12-37(28(38)18-35)24-4-2-3-23(30)14-24/h2-10,13-15,19H,11-12,16-18H2,1H3
InChIKey
MJSIQIQTEIQMNA-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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