Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXW2L1
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| Drug Name |
N-((S)-1-((2S,3S)-2-ethyl-4-oxotetrahydrofuran-3-ylamino)-4,4-dimethyl-1-oxopentan-2-yl)thiophene-3-carboxamide
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| Synonyms |
CHEMBL512367
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C18H26N2O4S
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| Canonical SMILES |
CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC(C)(C)C)NC(=O)c2ccsc2
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| InChI |
InChI=1S/C18H26N2O4S/c1-5-14-15(13(21)9-24-14)20-17(23)12(8-18(2,3)4)19-16(22)11-6-7-25-10-11/h6-7,10,12,14-15H,5,8-9H2,1-4H3,(H,19,22)(H,20,23)/t12-,14-,15+/m0/s1
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| InChIKey |
DUVDFBHAXHAWFR-AEGPPILISA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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