Drug Information

Drug General Information
Drug ID
DXV7T3
Drug Name
3,5,7-trihydroxy-2-(2-hydroxyphenyl)-4H-chromen-4-one
Synonyms
Datiscetin; CHEMBL503168
Indication Discovery agent Investigative [1587926]
Formula
C15H10O6
Canonical SMILES
OC1=C(Oc2cc(O)cc(O)c2C1=O)c3ccccc3O
InChI
InChI=1S/C15H10O6/c16-7-5-10(18)12-11(6-7)21-15(14(20)13(12)19)8-3-1-2-4-9(8)17/h1-6,16-18,20H
InChIKey
WCNLFPKXBGWWDS-UHFFFAOYSA-N
Target and Pathway
Target(s) Estrogen receptor beta Target Info [1587926]
Induced myeloid leukemia cell differentiation protein Mcl-1 Target Info [1587926]
KEGG Pathway Estrogen signaling pathway
Prolactin signaling pathwayhsa04151:PI3K-Akt signaling pathway
MicroRNAs in cancer
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Apoptosis signaling pathway
CCKR signaling map ST
Pathway Interaction Database Plasma membrane estrogen receptor signaling
Validated nuclear estrogen receptor beta network
Validated nuclear estrogen receptor alpha networke2f_pathway:E2F transcription factor network
Direct p53 effectors
IL6-mediated signaling events
HIF-1-alpha transcription factor network
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Ovarian Infertility Genes
Integrated Pancreatic Cancer Pathway
Nuclear ReceptorsWP254:Apoptosis
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
Apoptosis Modulation and Signaling
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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