Drug Information

Drug General Information
Drug ID
DXV2TC
Drug Name
N-[5-(2-Fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-4-trifluoromethyl-benzamide
Synonyms
CHEMBL1907841
Indication Discovery agent Investigative [1587926]
Formula
C24H17F4N3O2
Canonical SMILES
CN1C(=O)[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)N=C(c3ccccc3F)c4ccccc14
InChI
InChI=1S/C24H17F4N3O2/c1-31-19-9-5-3-7-17(19)20(16-6-2-4-8-18(16)25)29-21(23(31)33)30-22(32)14-10-12-15(13-11-14)24(26,27)28/h2-13,21H,1H3,(H,30,32)/t21-/m1/s1
InChIKey
XKDCRXFJHGOCJK-OAQYLSRUSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.