| Drug General Information |
| Drug ID |
DXU3R1
|
| Drug Name |
1-(5-((4-methoxybenzyloxy)methyl)thiophen-2-yl)-2,2,2-trifluoroethanone
|
| Synonyms |
CHEMBL496512
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Formula |
C15H13F3O3S
|
| Canonical SMILES |
COc1ccc(COCc2ccc(s2)C(=O)C(F)(F)F)cc1
|
| InChI |
InChI=1S/C15H13F3O3S/c1-20-11-4-2-10(3-5-11)8-21-9-12-6-7-13(22-12)14(19)15(16,17)18/h2-7H,8-9H2,1H3
|
| InChIKey |
MOFRXFLSGOVYKC-UHFFFAOYSA-N
|
| Target and Pathway |
| Target(s) |
Histone deacetylase 6 |
Target Info |
|
[1]
|
|---|
| Histone deacetylase 4 |
Target Info |
|
[1]
|
|
KEGG Pathway
|
Alcoholism
|
|
Viral carcinogenesishsa05034:Alcoholism
|
|
Epstein-Barr virus infection
|
|
Viral carcinogenesis
|
|
MicroRNAs in cancer
|
|
NetPath Pathway
|
IL2 Signaling Pathway
|
|
Pathway Interaction Database
|
Signaling events mediated by HDAC Class II
|
|
Signaling events mediated by HDAC Class Ihdac_classii_pathway:Signaling events mediated by HDAC Class II
|
|
Signaling events mediated by HDAC Class III
|
|
Signaling events mediated by HDAC Class I
|
|
Sumoylation by RanBP2 regulates transcriptional repression
|
|
Validated nuclear estrogen receptor alpha network
|
|
Reactome
|
NOTCH1 Intracellular Domain Regulates Transcription
|
|
Constitutive Signaling by NOTCH1 PEST Domain Mutants
|
|
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
|
|
Assembly of the primary ciliumR-HSA-2122947:NOTCH1 Intracellular Domain Regulates Transcription
|
|
WikiPathways
|
Ectoderm Differentiation
|
|
Neural Crest Differentiation
|
|
Cell CycleWP474:Endochondral Ossification
|
|
Cardiac Hypertrophic Response
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in lymphocytes - TarBase
|
|
miR-targeted genes in epithelium - TarBase
|
|
TarBasePathway
|
|
Cell Cycle
|
|
MicroRNAs in cardiomyocyte hypertrophy
|
| References |
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |
|---|
