Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXT1DU
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| Drug Name |
[(S)-5-[(Morpholine-4-carbonyl)-amino]-1-((R)-1-phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(4-fluoro-benzyl)-cyclobutylmethyl ester
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| Synonyms |
CHEMBL180528
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C33H43FN4O6
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| Canonical SMILES |
C[C@@H](NC(=O)C(=O)[C@H](CCCCNC(=O)N1CCOCC1)NC(=O)OCC2(Cc3ccc(F)cc3)CCC2)c4ccccc4
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| InChI |
InChI=1S/C33H43FN4O6/c1-24(26-8-3-2-4-9-26)36-30(40)29(39)28(10-5-6-17-35-31(41)38-18-20-43-21-19-38)37-32(42)44-23-33(15-7-16-33)22-25-11-13-27(34)14-12-25/h2-4,8-9,11-14,24,28H,5-7,10,15-23H2,1H3,(H,35,41)(H,36,40)(H,37,42)/t24-,28+/m1/s1
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| InChIKey |
BSRQMYCWEZBYDT-YWEHKCAJSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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