Drug Information

Drug General Information
Drug ID
DXR9EE
Drug Name
4-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid aminomethyl-amide
Synonyms
CHEMBL172109
Indication Discovery agent Investigative [1587926]
Formula
C27H35ClN6O2
Canonical SMILES
NCNC(=O)N1CCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)CC1
InChI
InChI=1S/C27H35ClN6O2/c28-22-5-6-23-21(17-22)4-3-20-2-1-9-30-25(20)26(23)33-14-12-32(13-15-33)24(35)16-19-7-10-34(11-8-19)27(36)31-18-29/h1-2,5-6,9,17,19,26H,3-4,7-8,10-16,18,29H2,(H,31,36)
InChIKey
XJVLIHWJSFYQBB-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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