Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXQ4YQ
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| Drug Name |
N-((S)-1-((R)-2-(benzyloxy)-1-cyanoethylamino)-4-methyl-1-oxopentan-2-yl)-1H-indole-2-carboxamide
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| Synonyms |
CHEMBL207827
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H28N4O3
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)N[C@@H](COCc3ccccc3)C#N
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| InChI |
InChI=1S/C25H28N4O3/c1-17(2)12-22(29-25(31)23-13-19-10-6-7-11-21(19)28-23)24(30)27-20(14-26)16-32-15-18-8-4-3-5-9-18/h3-11,13,17,20,22,28H,12,15-16H2,1-2H3,(H,27,30)(H,29,31)/t20-,22+/m1/s1
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| InChIKey |
DZMBJKYEIMVZSF-IRLDBZIGSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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