Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXPW0I
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| Drug Name |
[(S)-1-((2S,3S)-2-Isobutoxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester
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| Synonyms |
CHEMBL31363
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H29N3O5
|
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| Canonical SMILES |
CC(C)CO[C@@H]1NC(=O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc3ccccc3
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| InChI |
InChI=1S/C24H29N3O5/c1-16(2)14-31-23-20(22(29)27-23)26-21(28)19(13-17-9-5-3-6-10-17)25-24(30)32-15-18-11-7-4-8-12-18/h3-12,16,19-20,23H,13-15H2,1-2H3,(H,25,30)(H,26,28)(H,27,29)/t19-,20+,23-/m0/s1
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| InChIKey |
VGKJNJDNQCLECA-MZKRTTBSSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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