Drug Information

Drug General Information
Drug ID
DXP4RG
Drug Name
6-(((6-cyano-2'-(trifluoromethyl)biphenyl-3-yl)(1-methyl-1H-imidazol-5-yl)methoxy)methyl)-2-((tetrahydrofuran-2-yl)methylamino)nicotinonitrile
Synonyms
CHEMBL183372
Indication Discovery agent Investigative [1587926]
Formula
C31H27F3N6O2
Canonical SMILES
Cn1cncc1C(OCc2ccc(C#N)c(NCC3CCCO3)n2)c4ccc(C#N)c(c4)c5ccccc5C(F)(F)F
InChI
InChI=1S/C31H27F3N6O2/c1-40-19-37-17-28(40)29(42-18-23-11-10-22(15-36)30(39-23)38-16-24-5-4-12-41-24)20-8-9-21(14-35)26(13-20)25-6-2-3-7-27(25)31(32,33)34/h2-3,6-11,13,17,19,24,29H,4-5,12,16,18H2,1H3,(H,38,39)
InChIKey
WISKOZINSNUMIP-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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