Drug Information

Drug General Information
Drug ID
DXO8YU
Drug Name
4-{5-[4-(3-Chloro-phenyl)-3-oxo-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-2-[3-(2-hydroxy-ethoxy)-phenoxy]-benzonitrile
Synonyms
CHEMBL283203
Indication Discovery agent Investigative [1587926]
Formula
C30H28ClN5O4
Canonical SMILES
OCCOc1cccc(Oc2cc(Cn3cncc3CN4CCN(C(=O)C4)c5cccc(Cl)c5)ccc2C#N)c1
InChI
InChI=1S/C30H28ClN5O4/c31-24-3-1-4-25(14-24)36-10-9-34(20-30(36)38)19-26-17-33-21-35(26)18-22-7-8-23(16-32)29(13-22)40-28-6-2-5-27(15-28)39-12-11-37/h1-8,13-15,17,21,37H,9-12,18-20H2
InChIKey
MOLIDNVFZBNVNE-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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