Drug Information

Drug General Information
Drug ID
DXO8W1
Drug Name
(1R,8R,9S,13S)-11-[2-(2-methoxyphenyl)prop-2-enoyl]-1-(4-methylphenyl)-11-azatetracyclo[6.5.2.0^{2,7}.0^{9,13}]pentadeca-2,4,6-triene-9-carboxylic acid
Synonyms
RPR-130401; CHEMBL446112
Indication Discovery agent Investigative [1587926]
Formula
C32H31NO4
Canonical SMILES
COc1ccccc1C(=C)C(=O)N2C[C@@H]3[C@](C2)([C@@H]4CC[C@@]3(c5ccc(C)cc5)c6ccccc46)C(=O)O
InChI
InChI=1S/C32H31NO4/c1-20-12-14-22(15-13-20)31-17-16-26(24-9-4-6-10-25(24)31)32(30(35)36)19-33(18-28(31)32)29(34)21(2)23-8-5-7-11-27(23)37-3/h4-15,26,28H,2,16-19H2,1,3H3,(H,35,36)/t26-,28+,31-,32+/m1/s1
InChIKey
OMXJXAHPPQYWRS-OGCSMFTJSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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