Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXO4BX
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| Drug Name |
4-Methyl-2-(3-pyridin-4-yl-phenyl)-pentanoic acid cyanomethyl-(2,2,2-trifluoro-acetoxy)-amide
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| Synonyms |
CHEMBL125656
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H20F3N3O3
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| Canonical SMILES |
CC(C)CC(C(=O)N(CC#N)OC(=O)C(F)(F)F)c1cccc(c1)c2ccncc2
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| InChI |
InChI=1S/C21H20F3N3O3/c1-14(2)12-18(19(28)27(11-8-25)30-20(29)21(22,23)24)17-5-3-4-16(13-17)15-6-9-26-10-7-15/h3-7,9-10,13-14,18H,11-12H2,1-2H3
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| InChIKey |
CNLRAYSXYSIRHX-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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