Drug Information

Drug General Information
Drug ID
DXO0LH
Drug Name
2-(3-Chloro-phenoxy)-4-{5-[4-(3-chloro-phenyl)-3-oxo-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-benzonitrile
Synonyms
CHEMBL30349
Indication Discovery agent Investigative [1587926]
Formula
C28H23Cl2N5O2
Canonical SMILES
Clc1cccc(Oc2cc(Cn3cncc3CN4CCN(C(=O)C4)c5cccc(Cl)c5)ccc2C#N)c1
InChI
InChI=1S/C28H23Cl2N5O2/c29-22-3-1-5-24(12-22)35-10-9-33(18-28(35)36)17-25-15-32-19-34(25)16-20-7-8-21(14-31)27(11-20)37-26-6-2-4-23(30)13-26/h1-8,11-13,15,19H,9-10,16-18H2
InChIKey
NGKWYAFKLLDUKM-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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