Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXNS2V
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| Drug Name |
4'-(4-Fluoro-piperidin-4-yl)-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide
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| Synonyms |
CHEMBL200788
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H31FN4O2
|
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| Canonical SMILES |
FC1(CCNCC1)c2ccc(cc2)c3ccc(cc3)C(=O)NC4(CCCCC4)C(=O)NCC#N
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| InChI |
InChI=1S/C27H31FN4O2/c28-26(14-17-30-18-15-26)23-10-8-21(9-11-23)20-4-6-22(7-5-20)24(33)32-27(12-2-1-3-13-27)25(34)31-19-16-29/h4-11,30H,1-3,12-15,17-19H2,(H,31,34)(H,32,33)
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| InChIKey |
YWFBKMXYOUWUFR-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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