Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXM7XU
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| Drug Name |
4'-dimethylamino-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide
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| Synonyms |
CHEMBL383186
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H28N4O2
|
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| Canonical SMILES |
CN(C)c1ccc(cc1)c2ccc(cc2)C(=O)NC3(CCCCC3)C(=O)NCC#N
|
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| InChI |
InChI=1S/C24H28N4O2/c1-28(2)21-12-10-19(11-13-21)18-6-8-20(9-7-18)22(29)27-24(14-4-3-5-15-24)23(30)26-17-16-25/h6-13H,3-5,14-15,17H2,1-2H3,(H,26,30)(H,27,29)
|
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| InChIKey |
SKRZAIKACITCOZ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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