Drug Information

Drug General Information
Drug ID
DXM7AP
Drug Name
(10R,13S,17S)-3-Hydroxymethyl-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid diisopropylamide
Synonyms
CHEMBL24249
Indication Discovery agent Investigative [1587926]
Formula
C27H43NO2
Canonical SMILES
CC(C)N(C(C)C)C(=O)[C@H]1CCC2C3CC=C4C=C(CO)CC[C@]4(C)C3CC[C@]12C
InChI
InChI=1S/C27H43NO2/c1-17(2)28(18(3)4)25(30)24-10-9-22-21-8-7-20-15-19(16-29)11-13-26(20,5)23(21)12-14-27(22,24)6/h7,15,17-18,21-24,29H,8-14,16H2,1-6H3/t21?,22?,23?,24-,26+,27+/m1/s1
InChIKey
ACLUPLRKEIYGOI-LHNCMOAYSA-N
Target and Pathway
Target(s) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Target Info [1587926]
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Target Info [1587926]
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Allopregnanolone biosynthesis
Androgen biosynthesisPWY-7305:Superpathway of steroid hormone biosynthesis
Androgen biosynthesis
KEGG Pathway Steroid hormone biosynthesishsa00140:Steroid hormone biosynthesis
Prostate cancer
NetPath Pathway IL2 Signaling Pathway
PathWhiz Pathway Androgen and Estrogen Metabolism
Reactome Androgen biosynthesisR-HSA-193048:Androgen biosynthesis
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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